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Author

Sam Gandy

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Review Sep 2026

Rapid plaque clearance with anti-amyloid therapy for Alzheimer’s disease: in consideration of donanemab treatment duration from real-world cases

ABSTRACT To assess the possibility that individualized duration of donanemab treatment might enable early pausing of therapy, and to explore the possible utility of plasma P-tau217 as a biomarker for treatment response monitoring in real-time, two unrelated patients with early-stage Alzheimer’s disease were treated wit...

Jeongyeon Hwang, Alison C. Pietras, Georges Naasan et al. · 0 citations
Open access Aug 2026

miR155, triplicated in Down syndrome, regulates the development of neural stem cells and GABAergic interneurons in Alzheimer's disease mouse and human iPSC models

Dysfunctional microRNAs and GABAergic interneurons are features of Alzheimer's disease (AD). The role of neuronal microRNA155 (miR155), elevated in both AD and Down syndrome (DS), remains unknown.

Xiao-Dong Zhu, Jean-Vianney Haure-Mirande, Mesude Bicak et al. · 0 citations

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