Revisiting Macrophage Plasticity: From M1/M2 Polarization to Immune Modulation in Cancer Therapy.
Macrophages play a key role in organizing the immune system's response to different types of infections. Their remarkable plasticity enables them to develop and polarize into M1 (tumor-suppressing) and M2 (tumor-promoting) macrophages, in addition to Tumor-Associated Macrophages (TAMs). This thorough review examines ho...