#protein folding
Oct 2026
Efficient production of recombinant human serum albumin in Escherichia coli via oxidative folding mediated by the a domain of protein disulfide isomerase.
It is demonstrated that PDI(a)-mediated cis-fusion enables high-yield production of structurally native-like and functionally competent HSA in the bacterial cytosol and provides a practical platform for producing complex disulfide-rich proteins in E. coli.
R. Urade, Yuki Yamaguchi, K. Morishima et al.
· Journal of Bioscience and Bi... · 0 citations