Bovine myxovirus resistance protein (Mx)1, but not Mx2, mediates antiviral activity against human and avian influenza A viruses, including H5N1 clade 2.3.4.4b
ABSTRACT Highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b viruses have recently infected dairy cows in the United States, raising concerns about human spillover. The antiviral roles of bovine host defense factors, including myxovirus resistance proteins (bMx1 and bMx2), remain relatively understudied. We ex...