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Author

Sainan Wang

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2 papers indexed here

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Open access Sep 2026

EIDD-3525 is a broad-spectrum antiviral against alphavirus infection that targets the nsP4 RNA-dependent RNA polymerase

Mosquito-transmitted alphaviruses, including chikungunya (CHIKV), Mayaro, Eastern equine encephalitis, and Venezuelan equine encephalitis viruses, cause severe arthritic or neurologic disease in humans. There are currently no approved antiviral treatments against alphavirus infection. Here, we report that the purine ri...

Pei-Qi Yin, S. Choudhary, Sai-Nan Wang et al. · 0 citations
Open access Aug 2026

Pyridin-3-carbohydrazide strongly impairs Mayaro and Chikungunya virus replication in vitro

The data suggest that P-3-C exhibits a potential multitarget mechanism of action and highlight its antiviral activity against different alphavirus strains; however, this efficacy could be dependent on the cell line used.

N. Contreras, N. Cassani, Mikaela dos Santos Marinho et al. · 0 citations

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