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Oct 2026

A DNAzyme-Driven DNA Nanotracker for Orthogonal Dual-Channel Imaging of an Oncogenic Signaling Axis and Its Pharmacological Modulation

Pathway-targeted therapy has emerged as a promising strategy in cancer treatment, yet its efficacy relies on the accurate analysis of key signaling axes in living cells. The miR-140/FEN1 signaling axis, which is balanced in normal hepatocytes but dysregulated in hepatocellular carcinoma, represents a potential target...

Qian-Ying Zhang, Jing-Yi Zheng, Kai-Yu Liu et al. · 0 citations
Aug 2026

DNA nanoreactor-programmed interface modulation of Schottky junctions via etching for ultrasensitive dual-modal biosensing.

The sensitivity and accuracy of photoelectrochemical (PEC) biosensors are often constrained by high electron-hole recombination rates and reliance on a single detection mode. To address this limitation, an ultrasensitive PEC-colorimetric (CM) dual-mode biosensor has been designed based on DNA nanoreactor-programmed mod...

Hao-Yu Zhang, Min Zhao, Huijie Wang et al. · 0 citations

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