Author

Sagar Bhattacharya

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Open access Sep 2026

De novo pan-rhodamine binders for fluorescence microscopy from mammalian cells to extremophiles.

Fluorescent imaging in live cells is a cornerstone of life sciences. While natural fluorescent proteins have been engineered to enhance individual features, no existing tag combines ideal properties into a single system: high brightness, reversible binding, compact size, and stability across diverse conditions. Here, w...

Yu-Da Chen, Klaus Yserentant, Kibeom Hong et al. · Cell · 0 citations

Open access Aug 2026

Conserved catalytic motifs encode enzyme-like supramolecular peptide assemblies

The findings establish conserved catalytic motifs as a rich source of functional catalysts and demonstrate that they encode sufficient information to construct highly active supramolecular active sites independently of the globular protein fold demonstrate that complex catalytic function can emerge from remarkably simp...

Liam R. Marshall, Sagar Bhattacharya, Leonardo F. Serafim et al. · Research Square · 0 citations