Microbial cell-free DNA (mcfDNA) metagenomic next-generation sequencing (mNGS) is a promising technique for diagnosing infectious diseases. However, research on mcfDNA-based mNGS for diagnosing infections in liver transplantation (LT) recipients remains limited. The aim of this study was to evaluate the diagnostic...
Yongseop Lee, Eunki Min, Yu Jin Park et al.· Frontiers in Cellular and In...· 0 citations
Background
B-acute lymphoblastic leukemia (B-ALL) is a heterogeneous disease comprising more than 20 molecular subtypes defined by distinct gene expression profiles (GEPs) and genetic alterations. Subtypes primarily defined by GEPs remain challenging to identify using conventional cytogenetic and targeted molecular ass...
Seoyoung Lim, Yu Jeong Choi, Yu Jin Park et al.· Annals of Laboratory Medicin...· 0 citations
While the initial ctDNA detection rate correlated with pTNM stages, no significant association was found with other pathological features and ctDNA may be helpful for monitoring recurrence in patients with ESCC.
Hanmil Jang, Seung-Jung Han, S. Park et al.· Annals of Laboratory Medicin...· 0 citations
Overall, the findings suggest that panel-based ultra-deep NGS improves mutation detection, enhances diagnostic sensitivity, and may provide valuable prognostic information for MPN management, although larger prospective studies are needed to confirm these results.
Namsoo Kim, Yehyun Kang, H. W. Kook et al.· Cancers· 0 citations
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