Open access
Oct 2026
Single-Cell Multiplex Immune Biomarker Prediction from Histopathology Across Cancer Types and Clinical Endpoints
Abstract Background The spatial organization of cellular lineages within the tumor microenvironment governs disease progression and therapeutic response, but multiplexed spatial profiling remains costly, technically complex, and tissue-destructive. Routine hematoxylin and eosin (H&E) histopathology is inexpensive and w...
Usman Afzaal, Usama Sajjad, A. Akbar et al.
· Research Square · 0 citations