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Author

Saba Heydari Dehkordi

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Sep 2026

Agent-based modeling of tumor microenvironment suppression reveals the dominant barriers to anti-tumor immunity.

Cancer progression is driven by a tumor microenvironment (TME) that suppresses anti-tumor immunity through structural, cellular, and metabolic barriers. We developed a computational model to compare the relative impact of four major suppressive mechanisms: extracellular matrix (ECM) remodeling, PD-1-mediated checkpoint...

Saba Heydari Dehkordi, Abazar Arabameri · 0 citations

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