Novel bis(benzylidene)-6-methyl-2-thiouracil derivatives: design, synthesis, and molecular docking as potential antimicrobial agents against multidrug-resistant pathogenic bacteria
Pyrimidine-based heterocycles are crucial scaffolds in medicinal chemistry due to their extensive biological activity. This study involved the condensation of 6-methyl-2-thiouracil with various aromatic aldehydes under reflux in acetic and hydrochloric acid, resulting in the synthesis of a novel series of bis(benzylide...