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S. Thakral

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Open access Sep 2026

DEVELOPMENT, CHARACTERIZATION AND OPTIMIZATION OF DOLUTEGRAVIR SOLID DISPERSIONS USING PEG 6000 AND PVP K30: COMPARATIVE PROCESSING, FACTORIAL DESIGN AND TABLET DEVELOPMENT

The developed solid-dispersion approach substantially improved dolutegravir solubility and dissolution compared with the pure drug and physical mixtures, confirming the potential of solid dispersion for improving the formulation characteristics of dolutegravir.

Krupaben Pravinbhai Patel, S. Thakral · 0 citations

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