Immunoediting and precision biomarkers in prostate cancer: The emerging role of liquid biopsy, immune contexture and HLA genotype (Review)
The present review examines the emerging role of germline human leukocyte antigen class I genotype as a prognostic and predictive biomarker, explicitly integrating it with tissue-based immune contexture and liquid biopsy readouts by proposing immunoediting as a unifying mechanistic framework that links allele-specific antigen presentation to immune infiltration.