Author

S. Shrestha

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Open access Aug 2026

HuB/HuR inhibition decreases HPV E6 and E7 proteins, stabilizes p53, and induces integrated stress to impair cervical cancer cell growth.

Findings indicate that, by decreasing RBPs, while inducing DNA damage and ISR, SRI-42127 reduces HPV oncoproteins, restores p53 function in HPV+ CaCxs, thereby enhancing their sensitivity to conventional chemotherapy.

Xi-Sheng Liu, S. Shrestha, Y. Edwards et al. · Proceedings of the National... · 0 citations