Identification of Human Papillomavirus Integration Sites in the Human Genome Using NGS-Based Bioinformatics Analysis
The majority of cases of cervical cancer worldwide are caused by high-risk genotypes such as HPV-16 and HPV-18, making the human papillomavirus (HPV) one of the most clinically significant viral pathogens. The physical integration of viral DNA into the host genome, which sets off a series of genomic disruptions, is one...