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#protein folding Open access Oct 2026

Small viruses reveal bidirectional evolution between HK97-fold viruses and encapsulins via procapsids

Mining environmental metagenomics data, the authors show that small HK97-fold-encoding viral genomes bridge Duplodnaviria viral capsids and cellular protein shells, revealing bidirectional evolution in which viral procapsids enable the transitions between viral and metabolic compartments.

Abelardo Aguilar, Ingrid Miranda-Pérez, Omer Nadel et al. · 0 citations
Open access Sep 2026

Genome-wide characterization of host factors involved in single-stranded RNA and DNA phage infection pathways

Single stranded RNA (ssRNA) and single stranded DNA (ssDNA) bacteriophages represent a key component of the global virome, yet the host genetic networks supporting their infection cycles remain poorly understood. Here, we present a comprehensive, genome-wide mapping of the genetic landscape regulating infection cycles...

Isabella Murray, Roniya Thapa Magar, Denish Piya et al. · 0 citations

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