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Author

S. Rathore

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Sep 2026

AI-guided Designing of SARS-CoV-2 Main Protease (M pro ) Inhibitors: An Approach for Novel Antiviral Compound Discovery

Main protease (Mpro) enzyme of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) cleaves polyprotein pp1a and pp1ab at 11 sites, producing essential proteins of viral machinery, and possesses a conserved Cys145-His41 catalytic dyad. While different mutated strains of this virus are being identified, the...

Anand Kumar Pandey, S. Rathore · 0 citations

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