N-PHOSPHORYLATION OF AMINOTHIAZOLES AND AMINO-THIADIAZOLES WITH P(III)- AND P(V)-REAGENTS: SYNTHESIS, STRUCTURE, AND BIOLOGICAL ACTIVITY
This study investigates the N-phosphorylation of key mono- and diaminoheterocycles within the thiazole and thiadiazole series using dimethyl chlorophosphate (P(V)) and 1-tert-butoxy-N,N,N',N'-tetraethylphosphanediamine (P(III)) reagents. Eight novel derivatives were successfully synthesized and isolated. Reaction condi...