Candidate biomarkers of biologic aging include p16INK4a (p16) expression in peripheral blood T cells, a marker of cellular senescence, and whole-blood DNA methylation (DNAm) clocks, markers of epigenetic aging. Both have been associated with age-accelerating conditions, including cancer and chemotherapy, but their rela...
H. Muss, Can-Lan Sun, Yuan C. Ding et al.· GeroScience· 0 citations
Abstract Breast cancer is the most common cancer among women in the United States and the leading cause of cancer incidence and mortality among Hispanic/Latina (H/L) women. For women with a genetic predisposition to hereditary breast and ovarian cancer (HBOC), genetic counseling has been shown to aid in the decision-ma...
Daisy M. Montoya, Amanda F. Corpuz, Karla E. Gonzalez et al.· Cancer Research Communicatio...· 0 citations
BACKGROUND
Breast cancer genome-wide association studies (GWAS) have identified more than 200 susceptibility loci, but most studies are dominated by European and East Asian populations.
METHODS
We analyzed breast cancer GWAS summary statistics from African (AFR), East Asian (EAS), European (EUR), and Hispanic/Latina...
James L. Li, Maria Zanti, Jacob Williams et al.· JNCI Cancer Spectrum· 0 citations
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