Mechanistic understanding of viral protein-protein interactions enables global health security and pandemic preparedness, yet experimental characterisation remains difficult, costly, and often restricted to specialised laboratories. Here, we describe an in silico campaign using AlphaFold2 and AlphaFold-Multimer to pred...
Yew-On Han, Riya Narain, Razan Abbara et al.· bioRxiv· 0 citations
Detailed protocols for using Protein Data Bank in Europe (PDBe) PISA API, a new Application Programming Interface (API) for enhanced analysis of protein assembly interfaces, using an updated version of PISA software are presented.
G. D. Leines, Paulyna Magana, S. Nair et al.· Current Protocols· 0 citations
The Human Bindome is presented, a proteome-scale atlas of high-confidence in silico protein binder candidates that positions the Bindome as a resource of genetically encodable perturbagens for site-specific, modular control of protein function.
Julius Wenckstern, Anna M. Díaz-Rovira, Julia A. Kuhn et al.· bioRxiv· 0 citations
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