Author

S. Minot

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Open access Oct 2026

Dysregulation of epithelial differentiation architecture underlies field cancerization in head and neck cancer

Head and neck squamous cell carcinoma (HNSCC) has exceptionally high recurrence rates, exceeding 50%, contributing to mortality and morbidity. This recurrence rate is proposed to be due to field cancerization, a phenomenon where tumor-adjacent “field” tissue that appears histologically normal harbors molecular changes...

Claire B. Mills, Yin Huang, Chan-Mi Lee et al. · bioRxiv · 0 citations

Open access Oct 2026

The type VI secretion system governs strain maintenance in a wild mammalian gut microbiome

Bacteria inhabiting the mammalian gut coexist in dense communities where contact-dependent antagonism mechanisms are widespread. The type VI secretion system (T6SS) is an interbacterial toxin delivery pathway prevalent among gut Bacteroidales, yet its function in naturally evolved microbiomes remains poorly defined. He...

Beth A. Shen, K. Asfahl, Bentley Lim et al. · eLife · 0 citations