Impact of BRCA alterations on Androgen Receptor pathway inhibition treatment outcome in advanced prostate cancer.
Androgen Receptor Pathway Inhibitors (ARPIs) are frequently used to treat advanced prostate cancer (PCa). Understanding the impact of homologous recombination repair (HRR) alterations on ARPI treatment outcomes is critical for optimizing treatment. We conducted a retrospective analysis of pooled data from five randomiz...