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Open access Jul 2026

Modulation of the agonist and antagonist activity of peptidic FPR1 ligands through N-terminal modifications: A structural and functional analysis

Formyl peptide receptor 1 (FPR1) is a promising therapeutic target for the treatment of inflammatory and infectious diseases. Although multiple classes of peptides are known to modulate FPR1 activity, comprehensive studies systematically linking N-terminal modifications to binding, mechanism of action and functional ou...

S. Maskri, Denise Pajonczyk, Joana Massa et al. · 0 citations

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