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Author

S. Mas

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Sep 2026

Cognitive profiles in first-episode psychosis: The impact of genetics, environment, and cognitive reserve as risk and protective factors.

BACKGROUND Cognitive impairment is a core but heterogeneous feature of first-episode psychosis (FEP). Genetic liability, environmental exposures, and protective mechanisms such as cognitive reserve (CR) have been implicated in cognition. We examined whether cognitive profiles in FEP differed according to polygenic risk...

M. F. Forte, F. D. Rabelo-da-Ponte, Derek Clougher et al. · 0 citations
Open access Aug 2026

Polygenic profiles in youth with early-onset psychosis and offspring of schizophrenia or bipolar disorder patients.

The role of genetic factors shaping liability for psychosis remains unclear. Youth with first-episode, early-onset psychosis and youth at increased familial risk for psychosis show higher rates of co-occurring psychiatric diagnoses and cognitive difficulties than the general population. This study assessed polygenic sc...

I. Martínez-Serrano, A. G. Segura, María Ortuño et al. · 0 citations

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