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Author

S. Marrelli

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2 papers indexed here

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Open access Aug 2026

Impact of stroke on respiratory function and amyloid-β pathology in Tg-2576 mice

Background Stroke is a well-established risk factor for dementia, and many patients with Alzheimer's disease exhibit mixed neuropathology that includes both ischemic injury and amyloid-β (Aβ) accumulation. Breathing disturbances, such as apnea, have also been linked to cognitive dysfunction and accelerated dementia pro...

Yu-Xing Zhang, Ahmad El Hamamy, Zahid Iqbal et al. · 0 citations
Open access Sep 2026

Stress-induced helicase DHX36 controls neuroinflammation.

Neurons in the aging brain experience sustained inflammatory, proteostatic, and genotoxic stress, accompanied by the accumulation of non-canonical nucleic acid structures such as G-quadruplexes (G4s). Using a G4-binding probe and mass spectrometry, we identified the G4 helicase DHX36 enriched in the aged mouse brain, p...

V. J., Rocio Diaz Escarcega, Chun-Feng Tan et al. · 0 citations

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