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S. Marceglia

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Review Open access Sep 2026

Rethinking the role of animal models in adaptive deep brain stimulation: From feasibility to mechanistic and disease-modifying insights.

BACKGROUND Adaptive deep brain stimulation (aDBS) has emerged as an advanced neuromodulation approach capable of dynamically adjusting stimulation parameters based on real-time biomarkers, thereby overcoming the limitations of conventional continuous DBS (cDBS). While early animal studies were instrumental in establish...

M. Guidetti, H. Ali, A. Loh et al. · 0 citations

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