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S. Mahmood

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Open access Oct 2026

Childhood onset, indolent progression, and risk of hepatic rupture: the natural history of hereditary lysozyme amyloidosis.

BACKGROUND Lysozyme amyloidosis (ALys) is a rare systemic amyloidosis caused by pathogenic variants in LYZ. We describe the natural history and outcomes for this disease in the largest cohort yet published. METHODS All patients diagnosed with ALys at the National Amyloidosis Centre between 1988 and 2025 were included...

Jack E. Carruthers, J. Gilbertson, D. Rowczenio et al. · 0 citations

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