S. Ma

General-Purpose vs. Domain-Specific Large Language Models in Antibiotic Clinical Decision-Making: A Double-Blind Evaluation with a 2X2 Factorial Design

Domain-specific medical LLMs enhanced by CoT approach the antibiotic decision-making level of real physicians, with advantages in individualization and dosing precision, but notable deficiencies persist in antimicrobial stewardship ecological awareness and automated evaluation reliability, underscoring the continued indispensability of senior clinical expertise.