The JAK/STAT Signaling Pathway in Cancer: Mechanisms, Roles, and Therapeutic Implications
The JAK/STAT signaling pathway regulates processes such as proliferation, differentiation, survival, and immune responses. Dysregulation of this pathway is strongly correlated with the initiation and progression of several malignancies in humans. This pathway consists of Janus Kinases (JAKs) and Signal Transducers...