Mitochondria-targeted antioxidant Mito-Q induces granulosa cell apoptosis and impairs human pre-antral follicle growth in vitro.
The development of in vitro systems capable of supporting early human folliculogenesis holds significant promise for fertility preservation, particularly for patients who cannot undergo ovarian tissue transplantation. Mitochondria-targeted antioxidants have shown beneficial effects in later stages of oocyte maturation,...