Review
Open access
Jun 2026
Why antibody isotype matters for immunotherapy
The structural and functional properties of human IgG and IgA subclasses are reviewed with a focus on anti-CD20 rituximab in two- and three-dimensional models of human B-cell lymphoma, to highlight opportunities to refine antibody isotype selection for more individualized cancer immunotherapy.
S. Kleinau
· Antibody Therapeutics · 0 citations