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S. Kleinau

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Review Open access Jun 2026

Why antibody isotype matters for immunotherapy

The structural and functional properties of human IgG and IgA subclasses are reviewed with a focus on anti-CD20 rituximab in two- and three-dimensional models of human B-cell lymphoma, to highlight opportunities to refine antibody isotype selection for more individualized cancer immunotherapy.

S. Kleinau · 0 citations

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