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Review Open access Oct 2026

Semi-quantitative coronary computed tomography angiography plaque scores predict adverse cardiovascular outcomes: a systematic review and meta-analysis

Semi-quantitative Coronary Computed Tomography Angiography (CCTA) scoring systems - including the Segment Involvement Score (SIS), Segment Stenosis Score (SSS), CT-adapted Leaman score (CT-LeSc), Leiden score, and the Coronary Artery Disease-Reporting and Data System (CAD-RADS) are used to quantify atheroscleroti...

G. Mann, A. Sood, S. Khanna et al. · 0 citations
Open access Oct 2026

Ascending Aortic Calcium Identifies Patients at Risk Despite Normal Myocardial Flow, Perfusion and Coronary Calcium: A 13-Site Cohort Study

Background Patients with normal perfusion, normal myocardial flow reserve (MFR) and no coronary artery calcium (CAC) on myocardial perfusion imaging are considered low risk. Yet, adverse events still occur and no routinely reported imaging marker stratifies residual risk. This study aims to determine whether fully auto...

C. Spielvogel, A. Shanbhag, S. Khanna et al. · 0 citations
Sep 2026

Epicardial adipose tissue attenuation as an independent marker of cardiovascular outcomes in de novo heart failure (RECOVER-EAT).

BACKGROUND Epicardial adipose tissue (EAT) is a visceral fat depot implicated in cardiovascular disease. While EAT volume has been associated with risk, it provides limited information regarding adipose tissue composition. Computed tomography (CT)-derived EAT attenuation is a marker of adipose tissue composition, but i...

S. Khanna, N. McLellan, S. Vasanthakumar et al. · 0 citations
Open access Aug 2026

Coronary Plaque Burden and Plaque Composition in Long-Term Cancer Survivors: A Comparative CCTA Study

The increased risk of atherosclerotic cardiovascular disease in cancer survivors is not fully elucidated. Understanding the coronary plaque burden and composition in survivors could address this gap. To determine whether cancer survivorship is associated with greater coronary plaque burden and more adverse...

C. H. Soh, J. Wang, S. Khanna et al. · 0 citations
Open access Aug 2026

Clinical Reference Percentiles for AI-derived Epicardial Adipose Tissue: A Multicenter Study

Age- and sex-specific EAT percentiles provide a clinically interpretable framework for contextualizing automated EAT measurements and identifying patients at increased cardiovascular risk and identified elevated risk even among patients with normal BMI.

A. Kamagate, A. Shanbhag, M. Buchwald et al. · 0 citations

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