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Review Open access Sep 2026

The Multifaceted Roles of STAT6: Implications for Precision Immunotherapeutics

Abstract STAT6, located on chromosome 12, encodes a transcription factor whose SH2 domain is central to its activation. While classically a Th2 mediator, aberrant STAT6 activation is observed in diverse malignancies. This review focuses on the molecular and functional landscape of STAT6, primarily in cancer and tumor i...

Hiba Narvel, D. Nishizaki, S. Kato et al. · 0 citations
Review Open access Oct 2026

Evolution of Precision Oncology, Personalized Medicine, and Molecular Tumor Boards.

Evidence is accumulating to support feasibility and survival benefit in patients treated with matched therapy, and the incorporation of molecular targeted therapies and immunotherapy into the perioperative setting requires clinicians to understand the role of the MTB.

Yu Fujiwara, S. Kato, R. Kurzrock · 0 citations

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