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Author

S. K. Jha

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Review Open access Sep 2026

Mitochondrial metabolic plasticity in cancer: hybrid bioenergetic states and translational targeting in surgical oncology

Mitochondrial metabolism is increasingly recognized as an active determinant of tumor growth and cancer-cell adaptation rather than solely a source of cellular energy. Mitochondrial metabolism supports tumor anabolism, while mitochondrial DNA (mtDNA) alterations can affect respiratory chain function, redox homeostasis,...

Debdeep Chattopadhyay, R. Rajendran, Nida Mubin et al. · 0 citations
2026

Deciphering the oncogenic role of RRM2 in Glioblastoma multiforme and its modulation by plant derived compounds

Data make RRM2 an attractive therapeutic candidate in GBM and suggest some phytochemicals as potential inhibitors, which provide a logical basis for further experimental validation and creation of new, plant-tailored therapeutic interventions to manage GBM.

S. Singh, Pardeep Yadav, S. K. Jha · 0 citations

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