Author

S. Jois

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#protein folding Open access Oct 2026

Inhibition of RNA-m6A Methylation in Breast Cancer Cells Carrying TP53 R273H Mutant Reactivates Natural Killer Cells for Anticancer Immunity

Oncogenic p53 mutant proteins not only promote cancer cell proliferation but also evade immune destruction for tumor progression. Besides hijacking immune checkpoints, p53 mutants in cancer cells may deactivate anticancer immune cells for evasion. Herein, we report that p53 R273H mutation in human breast cancer cells d...

M. N. Amin, M. Mostaq, S. Jois et al. · Current Issues in Molecular... · 0 citations

Open access Sep 2026

Design of aptamer peptides for immunomodulation

To address the challenges posed by conformational isomerism in the sunflower trypsin inhibitor template due to proline-proline sequences in peptide design, two aptamer peptides were developed, SFTI-FGUA and SFTI-DMY, incorporating specific functional groups.

Arpan Chowdhury, Prajesh Shrestha, Vivekanandan Subramanian et al. · Journal of Enzyme Inhibition... · 0 citations