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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

S. J. van der Lee

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4 papers indexed here

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Open access Aug 2026

Carrying specific HLA alleles decreases the chance of reaching healthy old age

Human leukocyte antigen ( HLA ) genes regulate immune function and influence disease susceptibility, but their role in healthy aging is unclear. We investigated whether disease-associated HLA alleles affect the likelihood of becoming a cognitively healthy centenarian (CHC). Using imputed HLA genotypes from 36...

D. A. Sirvent, N. Tesi, M. Hulsman et al. · 0 citations
Open access Sep 2026

CSF proteomic quantitative trait loci mapping reveals genetic insights into Alzheimer’s disease

Many AD pQTLs in CSF were enriched in neuroimmune activation, suggesting a genetic basis for neuroimmune dysregulation in AD, and how genetic variation shapes protein expression in the central nervous system is highlighted.

L. Reus, Chen-Yang Jiang, N. Vilor-Tejedor et al. · 0 citations
Open access Jul 2026

snpXplorer: an interactive platform for haplotype-aware exploration and integrated annotation of GWAS data

Background Genome-wide association studies (GWAS) have identified thousands of loci associated with complex traits and diseases, yet translating these signals into biological insight remains challenging. Most associated variants are non-coding and reside in linkage disequilibrium (LD) blocks, where multiple correlated...

N. Tesi, G. Green, A. Salazar et al. · 0 citations

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