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S. Hosojima

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Open access Aug 2026

Sublethal disulfide stress facilitates TLR2-dependent NLRP3 inflammasome activation and pyroptosis in leukemia cells

The findings suggest that disulfide stress contributes to NLRP3 inflammasome activation and pyroptosis triggered by BLPs in leukemia cells, the first report linking disulfidptosis-associated disulfide stress to innate immune signaling.

S. Hosojima, Sheng-Hui Zhi, Yamato Tanabe et al. · 0 citations

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