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S. Hasselbalch

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Open access Sep 2026

Nigrostriatal imaging in patients with clinically uncertain Parkinsonian syndromes: a head-to-head comparison between SPECT, PET, and MRI.

PURPOSE Neurodegenerative parkinsonism is characterized by degeneration of the dopaminergic nigrostriatal pathways and a reduction in nigral neuromelanin. Dopamine transporter (DAT) imaging assesses presynaptic striatal dopaminergic function and is typically performed with [123I]FP-CIT SPECT-CT, but has recently also b...

G. Thomsen, K. Brendstrup-Brix, C. Svarer et al. · 0 citations
#protein folding Open access Sep 2026

Epitope placement tunes CSF tau biomarkers: Comparison of P-tau217 and BD-tau designs

Results show that, irrespective of the partner antibody, phosphorylated tau assays are more accurate than assays that also measure non-phosphorylated forms of the protein in differentiating Aβ + from Aβ − individuals, and indicate that BD-pTau217 may offer superior sensitivity for the early identification of AD patholo...

H. Gleerup, C. S. Musaeus, Cristiano Santos et al. · 0 citations

Binary classification of 18 F-flutemetamol PET using machine learning: comparison with visual reads and structural MRI

Whether a supervised machine learning technique, support vector machines (SVM), can replicate the assignments made by visual readers blind to the clinical diagnosis, which image components have highest diagnostic value according to SVM and how 18 F-flutemetamol-based classification using SVM relates to structural MRI-bas...

R. Vandenberghe, N. Nelissen, E. Salmon et al. · 0 citations

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