PURPOSE
Neurodegenerative parkinsonism is characterized by degeneration of the dopaminergic nigrostriatal pathways and a reduction in nigral neuromelanin. Dopamine transporter (DAT) imaging assesses presynaptic striatal dopaminergic function and is typically performed with [123I]FP-CIT SPECT-CT, but has recently also b...
G. Thomsen, K. Brendstrup-Brix, C. Svarer et al.· European Journal of Nuclear...· 0 citations
Results show that, irrespective of the partner antibody, phosphorylated tau assays are more accurate than assays that also measure non-phosphorylated forms of the protein in differentiating Aβ + from Aβ − individuals, and indicate that BD-pTau217 may offer superior sensitivity for the early identification of AD patholo...
H. Gleerup, C. S. Musaeus, Cristiano Santos et al.· Molecular Neurodegeneration...· 0 citations
Whether a supervised machine learning technique, support vector machines (SVM), can replicate the assignments made by visual readers blind to the clinical diagnosis, which image components have highest diagnostic value according to SVM and how 18 F-flutemetamol-based classification using SVM relates to structural MRI-bas...
R. Vandenberghe, N. Nelissen, E. Salmon et al.· 0 citations
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