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Open access Sep 2026

Defining a Safe Biopsy Deferral Strategy in Patients With Low-Risk or Equivocal MRI Findings Using Prostate-Specific Antigen-Based Metrics.

BACKGROUND Management of men with equivocal MRI findings remains uncertain, while low-risk MRI may still harbor clinically significant prostate cancer (csPCa). We examined whether prostate-specific antigen (PSA)-based measures could identify a low-risk subgroup suitable for biopsy deferral in patients with Prostate Ima...

O. Esengur, S. Harmon, Emma J. Stevenson et al. · 0 citations
Open access Aug 2026

Deep learning-based histologic classifiers enable molecular subtyping of metastatic prostate cancer.

Metastatic prostate cancer is a clinically and molecularly heterogeneous disease. Under the selective pressure of androgen receptor (AR)-directed therapies, resistant phenotypes frequently emerge, posing significant diagnostic and therapeutic challenges. Neuroendocrine prostate cancer (NEPC) is a clinically important p...

Zhi-Jun Chen, Erolcan Sayar, D. Guevara et al. · 0 citations

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