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Author

S. Haas

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Open access Aug 2026

The cortical microenvironment drives early immune organization and controls early osteoclastogenesis in bone healing

A specialized cortical niche is identified that coordinates immune and stromal cells to drive early osteoclast formation during fracture healing and shows that aging primarily impairs this supportive microenvironment rather than the cells themselves.

Anne Noom, H. Oktay, Duncan M. Morgan et al. · 0 citations
Open access Aug 2026

Perturb-seq identifies co-regulated gene programs shaping hematopoietic stem and progenitor cell function

Perturbation-derived co-regulation programs are established as an interpretable framework for linking genetic regulators, cell-biological processes and stem-cell-associated phenotypes by decomposing gene expression data from functional and clinical studies into program activity.

Joseph S. Bowness, Aina Bernal Martínez, Jan Bařinka et al. · 0 citations

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