Purkinje cell synapses in the cerebellar cortex require tight coordination between receptor trafficking and cytoskeletal remodeling to sustain synaptogenesis, structural plasticity, and motor learning. The glutamate δ2 receptor (GluRδ2), a hallmark component of parallel fiber-Purkinje cell synapses, depends on intracel...
Priyanka Dutta, Swagata Das, Pragya Bandyopadhyay et al.· Biochemical and Biophysical...· 0 citations
A novel signaling pathway involving FP10 and Rho2 is proposed that facilitates myosin-mediated remodeling of the actin cytoskeleton and is proposed to phosphorylate Myosin-IB during actin--myosin reorganization.
Avinash Kumar Gautam, Preeti Umarao, S. Gourinath· The FEBS Journal· 0 citations
The Ca2+ binding sites of proteins are critical for their function, particularly in processes such as signal transduction, enzyme regulation, and structural stability. In this study, the calcium-binding sites of NtEhCaBP1 (Entamoeba histolytica calcium-binding protein). This paper proposes Statistical Ranking Deep Lear...
P. Parwekar, S. Gourinath, Jaishree Jain et al.· PLoS ONE· 0 citations
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