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S. Gourinath

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Sep 2026

PIST couples actin cytoskeleton dynamics through a WH2-like actin-binding domain.

Purkinje cell synapses in the cerebellar cortex require tight coordination between receptor trafficking and cytoskeletal remodeling to sustain synaptogenesis, structural plasticity, and motor learning. The glutamate δ2 receptor (GluRδ2), a hallmark component of parallel fiber-Purkinje cell synapses, depends on intracel...

Priyanka Dutta, Swagata Das, Pragya Bandyopadhyay et al. · 0 citations
Jul 2026

Structural insight of the EhFP10-Rho2-Myosin-IB tricomplex reveals a novel signaling module for cytoskeleton remodeling in Entamoeba histolytica.

A novel signaling pathway involving FP10 and Rho2 is proposed that facilitates myosin-mediated remodeling of the actin cytoskeleton and is proposed to phosphorylate Myosin-IB during actin--myosin reorganization.

Avinash Kumar Gautam, Preeti Umarao, S. Gourinath · 0 citations
Open access Aug 2026

An efficient ranking deep neural network algorithm for the prediction of Ca2+ binding sites of the protein

The Ca2+ binding sites of proteins are critical for their function, particularly in processes such as signal transduction, enzyme regulation, and structural stability. In this study, the calcium-binding sites of NtEhCaBP1 (Entamoeba histolytica calcium-binding protein). This paper proposes Statistical Ranking Deep Lear...

P. Parwekar, S. Gourinath, Jaishree Jain et al. · 0 citations

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