Author

S. Goel

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Open access Oct 2026

Activation of the endocytosis pathway stratifies subtypes and therapeutic sensitivity in colorectal cancer.

Endocytosis regulates receptor trafficking and signaling, yet its role in colorectal cancer (CRC) remains unclear. We analyzed transcriptomic data from 15,025 CRC tumors to evaluate gene expression in clathrin-mediated endocytosis (CME) and the endosomal sorting complexes required for transport (ESCRT) pathway. Pathway...

H. Arai, A. Elliott, Yan Yang et al. · Oncogene · 0 citations

Review Oct 2026

Participation of Patients With Gynecologic Cancer in Phase I Clinical Trials: Experience From Two National Cancer Institute-Designated Comprehensive Cancer Centers.

PURPOSE Phase I trials are intended to define the safety of novel therapeutics, yet they offer alternative options long before they are approved. Limited data exist regarding access to and participation in phase I trials among gynecologic oncology patients. The purpose of this study is to assess the efficacy, toxicitie...

Anusha Adkoli, Charlotte Hadjadj, Krystle Vera et al. · JCO Oncology Practice · 0 citations