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Author

S. Glastras

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2 papers indexed here

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Open access Aug 2026

Dual inhibition of SGLT 1 and 2 by sotagliflozin alleviates intracellular sodium overload and improves cardiometabolic remodelling in uraemic cardiomyopathy.

AIMS Chronic kidney disease (CKD) is associated with uraemic cardiomyopathy characterised by early metabolic dysfunction. Elevated myocardial intracellular sodium (Naᵢ) has emerged as a driver of cardiometabolic remodelling, however, its role in CKD and therapeutic modulation remains unclear. We investigated whether du...

Megan Young, A. Karlstaedt, Sanushi Dambure et al. · 0 citations
Open access Sep 2026

Maternal Obesity Induces DNA Methylation Changes in the Kidneys and Blood of Rodent Offspring at Adulthood

Aim: To identify differentially methylated genes in offspring of obese versus lean mothers using a mouse model of maternal obesity. Background: Adverse conditions during fetal development predispose offspring to adult diseases, supporting the theory of fetal programming. DNA methylation is suggested as a mechanism by w...

B. P. Larkin, L. Nguyen, Naveen K. Parthiban et al. · 0 citations

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