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Author

S. Ghosh

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Aug 2026

Sustainably Synthesized Small Molecule Therapeutic Aggregates Attenuate Aβ-Induced ROS-Mitochondrial-Apoptotic Cascade in Alzheimer's Disease.

Alzheimer's disease (AD) is characterized by amyloid-β (Aβ) aggregation, oxidative stress, mitochondrial dysfunction, and progressive neuronal loss, yet effective disease-modifying therapeutics remain limited. Herein, we report the sustainable synthesis of two triphenylamine-based donor-acceptor (D-A) scaffolds, TPA-IM...

Priyam Ghosh, Sayantani Mukhopadhyay, Srinivas Rati et al. · 0 citations
Aug 2026

Therapeutic targeting of ROCK reverses EMT in lung cancer cells by impeding TAZ in Hippo signalling pathway.

The therapeutic potency of Lomitapide was established to target Hippo pathway through disrupting ROCK activity in EMT dynamics, evident by upregulation of epithelial markers and downregulation of mesenchymal markers, through western blotting, qRT-PCR and immunofluorescence studies.

Basab Ghosh, S. Ghosh · 0 citations

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