BACKGROUND
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, characterized by aggressive local invasion, early metastasis, and profound chemoresistance. Epithelial-mesenchymal transition (EMT) is a critical driver of these aggressive phenotypes, promoting tumor cell dissemination and...
Hajar Eftekhari, Zahra Tajik, S. Ghafouri-Fard· Cancer Treatment and Researc...· 0 citations
Background Parkinson’s disease (PD) is a multifactorial neurodegenerative disorder, and peripheral blood-based biomarkers may help capture disease-related molecular changes. Because protein prenylation is essential for Rab-mediated intracellular trafficking, we investigated whether genes encoding key prenylation enzyme...
Mohammad Jalal Tabatabaie, Solat Eslami, Atefe Abak et al.· IBRO Neuroscience Reports· 0 citations
The presented findings offer novel insights into the correlation of immune-related lncRNAs with pancreatic cancer progression and provide a foundation for future risk stratification modeling.
The findings have the potential to enhance genetic counseling and improve the classification of subtypes in RD, and demonstrate the utility of WES in the molecular diagnosis of retinal dystrophies, highlighting the importance of functional validation of newly identified variants.
elham alimoradi, Arash Salmaninejad, Parham Nejati et al.· Molecular and Cellular Probe...· 0 citations
This study expands the mutational landscape of JS in the Iranian population and underscores the utility of WES as a first-tier diagnostic tool for JS and related ciliopathies.
Sheyda Khalilian, Mohadeseh Fathi, Zahra Farbood et al.· Molecular Genetics and Metab...· 0 citations
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