Circular-pre-rRNA-dependent and -independent rRNA maturation pathways in Archaea.
Ribosome biogenesis in archaea is uniquely characterized by the formation of circular pre-rRNA intermediates, a process dependent on bulge-helix-bulge (bhb) motifs-structured RNA elements located in the processing stems flanking the rRNA and critical for cleavage and ligation by the tRNA splicing machinery. In this stu...