S. Emile

Trends and Survival Outcomes of Adjuvant Chemotherapy in Low-Risk Stage II Colon Cancer: A National Cancer Database Analysis.

BACKGROUND Guidelines recommend adjuvant chemotherapy for Stage II colon cancer with high-risk features. However, real-world adherence to these recommendations remains inconsistent. It is unclear whether select low-risk patients still derive survival benefit from adjuvant chemotherapy. OBJECTIVE Evaluate trends, pred...

Systematic Review and Meta-analysis of Perioperative Outcomes of Minimally Invasive and Open Pelvic Exenteration for Locally Advanced and Recurrent Colorectal Cancer.

BACKGROUND Pelvic exenteration (PE) is a complex surgery used for locally advanced and recurrent colorectal cancer. With most PE procedures performed via laparotomy, the role of minimally invasive surgery (MIS) in PE remains unclear. This systematic review aimed to assess perioperative outcomes of MI compared to open P...

A Propensity-Score Matched ACS-NSQIP Database Analysis of Primary Anastomosis With or Without Diversion for Acute Perforated Diverticulitis.

BACKGROUND Resection with primary anastomosis (RPA) has emerged as an accepted alternative to Hartmann's procedure for acute perforated diverticulitis with peritonitis, yet the need for routine diversion remains unclear. We compared short-term outcomes of RPA with and without diversion in this setting. METHODS We con...

Intraoperative Systemic Chemotherapy in Stage II-III Appendiceal Adenocarcinoma: A National Cancer Database Analysis