Author

S. Eichmüller

3 papers indexed here

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Open access Aug 2026

miR-155-5p drives coordinated tumor and macrophage reprogramming across multiple cancer entities

Investigation of whether miR-155-5p and miR-3535 represent regulators capable of driving coordinated functional reprogramming of both, tumor cells and macrophages found they modulate tumor-intrinsic immune checkpoint expression and functional macrophage polarization in a coordinated way.

Theresa Kordaß, Ann-Katrin Schlosser, Marijan Czygan et al. · BMC Medicine · 0 citations

Editorial Open access Jul 2026

The German National Strategy for Gene- and Cell-Based Therapies: Generating Impact by Employing a Novel Multi-Stakeholder Approach

The main goal of the German National Strategy for GCT is to ensure patient access to advanced therapies while strengthening Germany’s position as an international hub for biomedical innovation.

Christian Gallus, F. Ayuk, P. Beckhove et al. · Human Gene Therapy · 0 citations

Open access Aug 2026

Latent effector T cells mediate immunotherapy responses in the bone marrow microenvironment.

TFiT (tumor-reactive features in T cells), a transcriptional classifier that identifies tumor-reactive T cells and stratifies immunotherapy, but not chemotherapy, response across independent MM and AML cohorts, supporting its specificity for T cell-mediated tumor control.

N. Kehl, T. Wagner, Simon Steiger et al. · Cancer Cell · 1 citation