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Review Open access Oct 2026

Screen failure among patients consenting for early phase cancer clinical trials (EPCTs).

107 Background: EPCTs represent an important treatment option for patients with cancer. However, trials often have strict eligibility criteria and screen failures (SF) can limit enrollment. We sought to identify reasons for SF among potential EPCT participants, evaluate associations between SF and overall survi...

S. Durbin, Andrea Pelletier, N. Teeyapun et al. · 0 citations
Review Open access Oct 2026

Coping trajectories among early phase cancer clinical trial (EPCT) participants.

337 Background: The trajectory of coping strategies among EPCT participants likely shifts in response to treatment- and cancer-related challenges. However, little is known about how coping trajectories among EPCT participants correlate with patient factors, patient-reported outcomes (PROs), and clinical outcome...

Anh B. Lam, Andrea Pelletier, S. Durbin et al. · 0 citations
Review Sep 2026

Coping Strategies Among Early-Phase Cancer Clinical Trial Participants.

Associations of coping behaviors with patient outcomes found approach-oriented coping strategies correlated with higher QoL and lower distress, and interventions seeking to enhance outcomes in this population should target the diverse coping strategies used by EPCT participants.

Anh B. Lam, Andrea Pelletier, Cynthia Moore et al. · 0 citations

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