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S. Duparc

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Open access Sep 2026

Association between number of previous malaria episodes and treatment failure among children and adults with laboratory-confirmed Plasmodium infection treated with pyronaridine-artesunate in Gabon: a retrospective cohort study

Malaria remains a public health challenge in Gabon. Pyronaridine-artesunate is an effective oral treatment for uncomplicated malaria. In real-world context, treatment failures, though still rare, are expected to be more frequent than in clinical trials. Prior malaria episodes have been suggested as risk factor for trea...

G. Mombo-Ngoma, A. Meneguim, Rella Zoleko Manego et al. · 0 citations
Meta-analysis Open access Aug 2026

The effect of mefloquine dose on outcome of uncomplicated falciparum malaria treated with artesunate-mefloquine: a WWARN systematic review and individual patient data meta-analysis

A combination of mefloquine associated with artesunate (AS-MQ) was the first artemisinin-based combination therapy (ACT) to be used widely for acute uncomplicated P. falciparum malaria. Individual patient data from 31 studies of patients with uncomplicated falciparum malaria treated with various AS-MQ regimens (target...

E. Ashley, Emmanuel Baron, M. Bouyou-Akotet et al. · 0 citations

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